СИНДРОМ ГИЙЕНА-БАРРЕ, АССОЦИИРОВАННЫЙ С COVID-19 В РЕСПУБЛИКЕ САХА (ЯКУТИЯ)

Abstract

Guillain-Barre syndrome (GBS) is a rare, severe disease of peripheral nerves and nerve roots, which is usually caused by infections. Since the beginning of the pandemic of the new coronavirus infection COVID-19, numerous cases of Guillain-Barre syndrome have been presented in scientific publications, which developed in patients at various times after suffering the new coronavirus infection. The purpose of this study was to investigate the features of the development and course of GBS associated with COVID-19. Nine patients with an established diagnosis of GBS were examined, with six of them being infected with the SARS-CoV2 virus. A comparative study of the features of the course and severity of the disease was carried out in two groups: the main group – GBS associated with COVID-19; and the control group – GBS without COVID-19. Based on the data obtained, it can be said that GBS against the background of the new coronavirus infection develops more often in men over the age of 50 and proceeds much more severely than GBS unrelated to COVID-19. Axonal lesions with a longer and incomplete recovery of motor functions, with the development of severe respiratory failure requiring prolonged ventilation, were significantly more common in patients with COVID-19.