Abstract
Many women are suffering from a dramatic increase of metabolic syndrome after menopause(climacteric). The accumulation of fat in the visceral area has been described as one of main components of the metabolic syndrome. Obesity is the primary cause of metabolic syndrome. The aim of this study was to observe differences of anthropometric parameters describing obesity status of age group of 40th and 50th and the relationship between metabolic syndrome indicators and BMI, WHR, and %Fat. For these purpose 321 women with ages ranging from 40-59 year were volunteered to measure for determining the obesity status and blood lipid profiles. All subjects were asked for menopausal status, divided into two group and evaluated for BMI, WHR, %fat, serum lipid and body composition. The body composition of subjects was measured using bio-impedance method. Blood was drawn from the subject, centrifuged and stored for analysis. Blood lipid was analyzed using enzymatic method by SELECTRA XL(NETHERLAND). The results showed that postmenopausal women in 50`s show higher BMI, WHR, %fat, TC, LDL-C, TG compared with premenopausal women in 40`s but lower height, weight, HDL-C. WHR was more effective variable to describe obesity status BMI than BMI, in both 40`s and 50`s menopausal women. WHR and %Fat of premenopausal women in 40`s showed significant differences between each BMI stages (abcd). In addition WHR and %Fat of postmenopausal women in 50`s showed significant difference only between a and d, but no significant between b and c (ab=cd) existed. In present study, the correlation between metabolic syndrome indicator of 40`s and 50`s and BMI, WHR, %fat were examined. TC and LDL-C were mostly related with %Fat(40`s), WHR(50`s), HDL-C with BMI(40`s), %Fat(50`s), triglyceride with WHR(40`s), %Fat(50`s). In conclusion, women in 50`s showed significantly higher TC, LDL-C, TG and significantly lower HDL-C compared with 40`s. This may suggest that after menopause metabolic syndrome might increase independently with aging. BMI showed higher correlations coefficient with WHR than %Fat.
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