Abstract

Benign transient hyperphosphatasemia of childhood (TH, BTH, BTHC) is a condition characterized by a temporary significant increase in the level of alkaline phosphatase in healthy people. This condition is transient and it does resolve without treatment within 2 to 4 months, does not have any long-term consequences (according to the analysis of the bibliographical sources and the Authors’ own observations). BTH is most often detected in children under the age of 5 y/o with the peak under 2 years, however there are sporadic cases in adults observed. In addition, there are descriptions of familial cases of TH that are clinically identical to the sporadic ones. Authors present twelve own observations of BTH cases and the bibliographical review on the topic. The criteria for BTH diagnosing are formed and a benign course of this condition had been confirmed.

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