제주도 대장암 발생률 추세에 대한 연구

Abstract

Abstract The age-adjusted incidence rate (AAR) of colorectal cancer in Korea peaked in 2011 and then began todecline. However, the AAR of colorectal cancer in Jeju increased continually from 1999 to 2013. Compared with the16 major cities in Korea, the inhabitants of Jeju-do have a low cancer screening program participation rate, high alcohol consumption rate and high BMI. The present study aimed to provide a statistical basis for the lowering ofthe incidence of colorectal cancer in Jeju-do. The Jeju regional cancer institute data from 1999 to 2013 was usedto analyze the between Jeju-do and Korea using the Joinpoint Regression program (Statistical Methodology and Applications Branch, Surveillance Research Program, National Cancer Institute) Version 4.2.0 - April 2015. The AARof colorectal cancer in Jeju-do has being increasing because of the increase in the rates of male colon cancer (averageannual percent change 8.422%, p-value< 0.000), female colon cancer (AAPC 6.136%, p-value< 0.000), male rectal cancer (AAPC 4.221%, p-value 0.003) and colon cancer in people aged over 50 years (AAPC 7.986% p-value< 0.000). The results of this study suggest that the treatment of precancerous lesions of the male rectum and lowering of the incidence of colon cancer in people aged over 50 years are necessary to reduce the colorectal cancer incidencerate in Jeju-do.