Abstract

Purpose.. To increase the effectiveness of treatment of patients with permanent nystagmus with injections of botulinum toxin type A (BTA). Material and methods. Treatment was carried out in 25 patients (50 eyes) with permanent oscillatory movements nystagmus of various amplitude using injections of BTA into oculomotor muscles. The observation period was 6 months. Results. Month after BTA injections, the frequency of nystagmus decreased in 2 patients (8.0%), and a decrease in the amplitude of oscillatory eye movements was noted in 21 patients (84.0%). By the end of the follow-up period, after 6 months, 2 patients (8.0%) had no signs of nystagmus, 19 (76.0%) children had a positive effect such as decrease in the frequency and amplitude of oscillatory eye movements. In 4 patients (16.0%), the use of BTA was commented as unsatisfactory, since after 3 months of observation, a regression of positive dynamics was revealed. Conclusion. The method of chemodenervation of oculomotor muscles using BTA showed high efficiency (84.0%) in the treatment of permanent nystagmus in children. This technique makes it possible to create physiological conditions for the formation of visual functions in children. Key words: nystagmus, botulinum toxin type A, chemodenervation, treatment of nystagmus

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