Abstract
Dystrophic diseases of the vulva (DDV) are a group of diseases that have not been fully studied and are characterized by pain, itching, dyspareunia, dysuria, which significantly reduce the quality of life of patients, leading to vegetative-vascular and neurological disorders. Despite many different approaches, the problem of treating vulvar DDV remains unresolved, and among clinicians there is no single approach to treatment, which was the basis for studying the effectiveness of photodynamic therapy (PDT) with local application of a photosensitizer in patients with DDV. As part of the study, 35 patients with DDV were examined and treated. REVIXAN-DERMA gel was used as a photosensitizer, irradiation of the vulva was carried out using a medical laser device "LAMI" with a wavelength of 660 nm. One month after PDT of the vulva, we noted a clinical recovery in 70% of patients (no complaints), a normal vulvoscopic picture was observed in 60% of patients – epithelialization of cracks and erosions, restoration of the thickness of the epithelium, restoration of normal skin pattern, in the remaining 40% patients – epithelization of cracks and erosions, a decrease in the area of damage, restoration of the thickness of the epithelium was noted, in 70% of patients the cytogram was within the normal range, cells with signs of intraepithelial changes and malignancy were not found, in 30% of patients – a small number of horny scales, cells with signs of intraepithelial changes and malignancy were not found. During the PDT procedure of the vulva, no complications or side effects were registered. Thus, the results of the study after the use of PDT of the vulva with local application of the photosensitizer REVIXAN-DERMA gel indicate the effectiveness, safety and prospects of the method in the treatment of degenerative diseases of the vulva.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: "Radiation and Risk" Bulletin of the National Radiation and Epidemiological Registry
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.