Abstract
Material was obtained from 21 cadavers 16 males, ageing range 80-92, mean 84, 5 females aging range 80-81, mean 81 for the histochemical study. Materials of females, ageing range 63-71, mean 67 were utilized for three morphometric dimensional reconstruction, and those of males, aging range 68-75, mean 71 for enzymic stained study (Avidin-Biotin Peroxidase complex method). The whole of the thyropharyngeus muscle and cricopharyngeus muscle was removed from each cadaver. In addition, the configurational analysis of the larynx and hypopharynx during dry swallowing in young adult subjects was assessed using a small caliber fiberoptics and CCD-fiberoptics.Results were compared with values from samples of hypopharyngeal histopathology and configuration in young adult cadavers and subjects. Degeneration due to ageing of the muscle fiber was clarified by means of measuring the diameter of each muscle fiber. The diameter of the thyropharyngeus muscle fiber (Tp) and cricopharyngeus muscle fiber (Cp) was influenced by ageing from (mean) 16.07μm to 13.14μm and (mean) 16.18μm to 13.96μm individually. The type I fiber of both muscles was refractory to the aged degeneration compared with the type II fiber. The mitochondria near I-band was degenerated and contained the lipofuscin granules which was assured by an electron microscopic study.
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