Abstract
Uveal melanoma is the most common primary intraocular malignant tumor among the adult population, its prevalence is more than 85% in the structure of all melanomas. Worldwide, the annual incidence of uveal melanoma is 6 cases per 1 million people. Despite the ongoing search for an effective treatment for uveal melanoma, there has not been a significant increase in the 5-year survival rate (~80%) in recent years, and approximately 50% of patients develop metastatic disease. The aim of this research was to analyze the clinical case of a female patient with metastatic uveal melanoma diagnosed with a metastatic lesion 28 years after enucleation. Modern possibilities of complex diagnostics using clinical, histopathological, cytogenetic and immunohistochemical markers determine the possibilities of performing polychemotherapy and determine the prognostic criteria for the life expectancy of patients.
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