Abstract

The purpose of this study was to investigate the biological activities of water soluble browning reaction products(WS-BRPs) isolated from korean red ginseng. Antioxidative activities of WS-BRPs were examined with the various systems. Three different fractions prepared by osmolytic treatment of WS-BRP(fraction L, S-1 and S-2) were found to have an ability to donate hydrogen to DPPH and also exhibited the inhibitory activities in lipid peroxidation, consumption of oxygen and protein oxidation of mitochondrial fraction. Especially, L had the strongest activity of these three WS-BRPs in scavenging free radicals. Lipid peroxidation showed the antioxidant effect on linoleic acid oxidation inhibition ratio of 22.5%, 31.7%, 31.9% and 33.5%, respectivity. And the consumption of oxygen was strongly inhibited by 49.52%, 62,44,97.54%. But three WS-BRPs shuwed weak inhibitory activity on lipid peroxidation in rat hepatic microsomes.

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