Abstract
The problem of urinary incontinence is multidisciplinary. Patients with this problem get an appointment with therapists, general practitioners, pediatricians, urologists, gynecologists, neurologists. Real clinical practice is currently characterized by a significant increase in clinical situations, when it is difficult to talk about the presence of only one disease in a patient, and in most clinical cases the patient has a concomitant or combined pathology. Arterial hypertension and diabetes mellitus are among the most common somatic diseases. To analyze the influence of these diseases on the development of urinary incontinence, we searched the MEDLINE and elibrary.ru databases. Metabolic syndrome is a consolidated manifestation of the comorbidity of hypertension, diabetes mellitus and obesity. There is only sporadic information on the possible effect of drug therapy for comorbid pathology, in particular antihypertensive therapy, on the symptoms of urinary incontinence. Drugs used to treat urinary incontinence can affect comorbid conditions in patients. In patients with urinary incontinence and the presence of comorbid conditions, which are also risk factors for urinary incontinence, the choice of a drug for the treatment of urinary incontinence with minimal effect on comorbid comorbid pathology is relevant. The results of numerous studies demonstrate that the use of trospium chloride allows for effective and safe pharmacotherapy of urinary incontinence, including in comorbid patients.
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