Abstract
Обзор рекомендаций Американского общества клинической онкологии (ASCO) и Американского общества по инфекционным болезням (IDSA) по антимикробной профилактике у иммунокомпрометированных взрослых пациентов, получающих терапию в связи со злокачественными новообразованиями
Highlights
Review of the American Society of Clinical Oncology (ASCO) and Infectious Diseases Society of America (IDSA) clinical practice guidelines on antimicrobial prophylaxis for adult patients with cancer-related immunosupression
Patients undergoing cytotoxic chemotherapy and hematopoietic stem-cell transplantation are at risk for infection
The risk of infections increases with the depth and duration of neutropenia, with the greatest risk occurring in patients who experience profound, prolonged neutropenia after chemotherapy, which is most likely to occur in the period before engraftment during hematopoietic stem-cell transplantation and after induction chemotherapy for acute leukemia, as well as in other situations that are accompanied by deep long-term neutropenia
Summary
FDA updates warnings for fluoroquinolone antibiotics. https://www.fda.gov/newsevents/ newsroom/pressannouncements/ucm513183.htm. Engelhard D., Cordonnier C., Shaw P.J., et al Early and late invasive pneumococcal infection following stem cell transplantation: a European Bone Marrow Transplantation survey. Engelhard D., Akova M., Boeckh M.J., et al Bacterial infection prevention after hematopoietic cell transplantation. Kontoyiannis D.P., Marr K.A., Park B.J., et al Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: Overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) database. Sun Y., Meng F., Han M., et al Epidemiology, management, and outcome of invasive fungal disease in patients undergoing hematopoietic stem cell transplantation in China: A multicenter prospective observational study. Robenshtok E., Gafter-Gvili A., Goldberg E., et al Antifungal prophylaxis in cancer patients after chemotherapy or hematopoietic stem-cell transplantation: Systematic review and meta-analysis.
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