Abstract
The electron paramagnetic resonance method was used to study the intensity of nitric oxide production by analyzing the amount of NO-containing paramagnetic complexes in the heart, liver, and spinal cord tissues of 7- and 16-week-old rats growing under restricted mobility conditions. Nitric oxide production was assessed by the intensity of the EPR signal belonging to the (DETC)2-Fe2+-NO complex. The results obtained show that growth under conditions of restricted motility leads to an increase in NO production in all organs under study, with the greatest increase observed in 7-week-old rats.
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