Abstract
This literature review is devoted to the modern technology for treating herpetic eye infections – genome editing. The importance of the problem lies in the fact that currently there are no drugs that can destroy herpes viruses, and their lifelong persistence in the human body can lead to relapses with the development of blindness and low vision. The review describes the results of preclinical studies of the use of CRISPR-associated protein 9 (CRISPR/Cas9) technology in the treatment of herpes eye infection, as well as when using this technology in the clinic for corneal transplantation in cases of severe stromal keratitis. Key words:: eye, herpes simplex virus type 1, treatment, genome editing
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