Abstract
A model of plasma membrane folding formation under the action of longitudinal and transverse mechanical forces applied to it is presented. These forces arise due to changes in protein-lipid and lipid-lipid interactions in the membrane and the submembrane spectrin-actin-ankyrin network under changing external conditions (temperature, pH), and interaction with ligands. A model of a linear elastic continuum is used. It is established that the amplitude of the height of folds is directly proportional to the amplitude of the applied distributed transverse forces and inversely proportional to the longitudinal stress. It is shown that if the value of the longitudinal stress exceeds a certain critical value, then the membrane folds are modulated by subfolds. The distributed transverse force has the same wavelength as the membrane folds. The results of mo-deling at a qualitative level explain the results of atomic force microscopy of the surface of erythrocyte membranes during their interaction with stress hormones and androgens.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Proceedings of the Russian higher school Academy of sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
