Abstract
Distal symmetric sensory-motor diabetic polyneuropathy (DPN) – the most common variant of diabetic neuropathy, which is expressed by more than 50 % of patients with diabetes mellitus (DM) 1 and type 2. The pathogenesis of DPN is the damaging effect of chronic hyperglycemia. Based on this key trends in the pathogenetic treatment of DPN are the normal levels of blood glucose, improved tissue perfusion and oxygen consumption, improve the rheological properties of blood, to restore normal energy balance, reducing the severity of oxidative stress.
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