벌유충 분말 서플리먼트의 이명에 대한 임상적 연구

Abstract

Abstract Objectives : The primary purpose of present study is to evaluate the effe ct of a supplement of Bee Larva on tinnitus. the second is to comparatively evaluate safety of thi s supplement. Methods : Among those patients who visited Semyung Oriental Medical Ce nter from January 11st, 2010 to February 20th, 2010, we screened 45 patients considered suitabl e for this study after some examinations and consent of the patients. they were devided into 2 groups. Group A took 5 tablets of this supplement everyday for 4 weeks, group B, placebo, in the same way. for 4 weeks, we checked changes in intensity, duration, extent of tinnitus on daily life and sleep and THI(Tinnitus Han dicap Inventory) score. to evaluate safety of this supplement, adverse events, assessment of vital sign, hematolog ic examination were recorded. Result : Through 4 weeks of the clinical trial, we found that this supplement is effective on tinnitus and it improves intensity, duration and extent (its influence on daily life) of tinnitus, influence of tinnitus on sleep and THI score more effectively than the placebo drug. Also, in the assessment of the safety of the study the supplement of bee Larva and placebo drug, there were no adverse events and side effects over the average which need treatment for it. Moreover, there were not any abnormal findings in change of blood pressure and hematologic examination. Conclusion : According to this experiment, we confirmed that the suppleme nt of bee Larva can be used effectively and safely on tinnitus.Key words : Tinnitus; Bee Larva; THI; supplement; clinical study