Расширение арсенала диагностического мониторинга пациентов с увеитами

Abstract

Goal. To evaluate the structure of somatic and ophthalmological polymorbidity, etiology, and course of the disease in patients with uveitis on the basis of clinical, laboratory, and instrumental research methods based on the data of a 24-hour ophthalmological hospital. Materials and methods. We examined 655 patients diagnosed with uveitis who were treated in the adult ophthalmology department of the GBUZ TO OKB No. 2 for the period from 2017 to 2019. All patients underwent standard laboratory, clinical, and instrumental examinations. In addition, the leukocyte index, a marker of viral infections (MVI), was determined. Results. The average age of patients with uveitis was 51 years, with a significant (p < 0.05) prevalence of cases of anterior uveitis over posterior and panuveitis. Pathology of the cardiovascular system occupies a leading position in the structure of somatic polymorbidity, mainly in women. Gender dependence in patients with rheumatic diseases, pathology of the gastrointestinal tract and endocrine system, bronchopulmonary pathology, cancer, and HIV infection was not detected. A method of early diagnosis of the nature of the course of the inflammatory process of the vascular membrane (acute or chronic) by determining the age of the patient and the indicator of MVI is proposed. Conclusions. Modern monitoring of the diagnosis of this disease and adequate empirical treatment with antiviral drugs with an extended spectrum of activity until the results of ELISA are obtained, followed by treatment correction, will prevent early disability of the population and improve the quality of life.