Abstract
Bone metabolism disorders during menopause, which occur against the background of decreasing estrogen levels, stimulate the early development of osteopenia and osteoporosis. Bone homeostasis disorders in menopause may be impacted by a variety of causes, including (1) metabolic disorders of other types of connective tissue (in particular, joints, ligaments, skin and its appendages), (2) complex hormonal imbalance (including insulin resistance), (3) deficiency of osteotropic macro- and microelements (calcium, magnesium, copper, zinc, boron, etc.). Measurements of blood levels of these elements are informative biomarkers for assessing bone health in patients, and supplementation with these elements is an effective therapeutic strategy for osteoporosis and other connective tissue disorders in perimenopausal women. Key words: menopause, bone homeostasis, osteopenia, osteoporosis, Calcemin Advance
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