Abstract

Experiments with rats demonstrated that 2 new nicotinic acid derivatives LKhT 8-20 and LKhT 9-20 at a dose of 50 mg/kg have equally a distinct anti-motion sickness activity increasing by 2 times, when compared to the control, food consumption following rotation. The vestibuloprotective effect was higher in comparison with mexicor (ethylmethylhydroxypyridine succinate) at similar dose in 1.5 and 1.4 times, respectively.

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