Abstract

Research relevance: fatty liver disease is one of the common worldwide disorders and is a public health problem, with obesity and other metabolic disorders. Research methods and materials: article is based on the publications review concerning fatty liver degeneration in cardiovascular diseases. Research objectives: to identify the course, etiology, and clinical picture of metabolic and immune changes in fatty liver degeneration. Research results: pathogenic factors associated with fatty liver disease are multifactorial and include inflammation, adipokines, intestinal dysbiosis, oxidative stress, which are established signs of cardiovascular disease. Conclusions: The accumulation of fat in the liver may be associated with ectopic adipose tissue, including myocardial fat and adipose tissue surrounding the heart, which is a central aspect.

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