Белки теплового шока в нормальной физиологии насекомых

Abstract

Heat shock proteins are molecular chaperones responsible for proper protein folding and maintenance of cellular homeostasis. Heat shock proteins have long been believed to be essential for the development of a cellular response to heat shock, chemicals, desiccation, hypoxia, and other stressors. However, more and more evidence of the participation of heat shock proteins in the normal physiology of mammals and insects has recently appeared. The article reviews the involvement of heat shock proteins in the development, aging, diapause and functioning of the muscular, visual, and nervous systems in insects. Small heat shock plays an important role in all these processes. An increase in the expression of small heat shock proteins contributes to a longer lifespan in Drosophila mutants. The activity of heat shock proteins from the Hsp70 family in insects is associated with the development and functioning of the visual and central nervous systems, in particular, conditioned reflex activity in Drosophila. Heat shock proteins are activated in diapause depending on the phylogenetic position, developmental characteristics, and ecology of the insect.