Abstract

According to various authors, obesity programming factors act at the early stages of development: fetus – newborn – young child. High birth weight indicators may be due to a genetic predisposition to obesity in childhood and contribute to an imbalance of energy systems in adults. We conducted a longitudinal observational study, during which we analyzed the absolute numbers and frequency of births of large­weight newborns for 20 years (the period from 2002 to 2021) in Health Care Institution “5th City Clinical Hospital of Minsk”. The purpose of our study was to evaluate the anthropometric characteristics of mothers of large­weight newborns in the pre­ and gravidar period, as well as to study the features of early neonatal adaptation of these children. It was found that the birth rate of large­weight children has no tendency to decrease, as well as to increase. Metabolic syndrome and hypothyroid state of the mother may be predictors of the formation of macrosomia in the fetus. Large­ weight newborns belong to the risk group for the development of hypoglycemia in the early neonatal period. Conflict of interests. The authors declare that there is not conflict of interests.

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