Abstract
ENT finding by patients with P- thalassemia; Polina Nencheva, Petar Rouev, Mirela Rangelova, Denka Stoyanova, Dimitar Mihailov Introduction: The thalassemic syndromes are heterogeneous group of diseases. By this kind of haematological disorders the synthesis of p-polypeptid chains is decreased or missing. Except the thalassemic face and other symptoms of the P-thalassemia there are also some kinds of otorhinolaringological symptoms. Objective: The aim of this study is to determine the ENT status by patients with P-thalassemia under regular haemotransfusions and chelating therapy. Study design: Multicentre prospective research - ENT Clinic, Paediatric Clinic, Therapeutic Clinic, Medicine Faculty, Stara Zagora; 6-th Therapeutic Department, District Hospital "Prof. S. Kirkovich", Stara Zagora; Sector of Thalassemia, Paediatric Hospital, Sofia; Sector of Thalassemia, National Centre of Transfusiology, Sofia. Material and Methods: 63 patients with P-thalassemia under regular haemotransfusions and chelating therapy were examinated; ENT examination and audiometry. Results: I patient with chronic serous otitis media and hearing loss; 3 patients with hypertrophy of the pharyngeal tonsils; 16 patients with hypertrophy of the tonsils; 5 patients with septum deviation; 60 patients of the patients with hypohromic nasal mucosa.
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