Abstract

Purpose: The purpose of this study was to evaluate the effect of a mixture of ARL oils, Agastache rugosa, Rosemarinu officinalis, and Lavandula angustifolia on atopic dermatitis (AD) model on NC/Nga mice. Methods: Twenty-four, 6 week-NC/Nga mice were assigned to a control group (C, n=8), an AD-induced group (E, n=8), and an ARL oil-treated group (E, n=8) that had two treatments per day for 6 days. Epidermis thickness, total amount of collagen and expression of TGF-<TEX>${\beta}$</TEX> in the AD induced mice were measured. Results: The ARL oil-treated group showed a significantly decreased epidermis thickness, and a greater amount of collagen and expression of TGF-<TEX>${\beta}$</TEX> compared with the AD-induced group. Conclusison: ARL oil may be a putative resources for care or treatment of AD in the view of nursing intervention.

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