НЕВУС КЕННОНА: ФАКТОРЫ РИСКА, КЛИНИЧЕСКАЯ КАРТИНА, ДИАГНОСТИКА

Abstract

Abstract. Diseases of the oral mucosa are quite common, but their differential diagnosis is very difficult. One of the types of diseases of the oral mucosa are diseases accompanied by a violation of keratinization - the so-called "white manifestations" on the oral mucosa, some of which can lead to the development of cancer. Cannon’s spongy nevus is a disease whose main symptom is parakeratosis, which is a violation of the keratinization of the oral mucosa. The purpose of the study was to study the clinical picture of Cannon's spongy nevus, to identify differential diagnostic criteria and risk factors for exacerbation of this disease. Materials and methods: 23 patients aged 18-44 years of both sexes with a diagnosis of Cannon's spongy nevus were under our supervision. Patients underwent a survey (including a detailed collection of complaints, anamnesis of life and disease), a daily objective examination for three weeks, fluorescent diagnostics using a Wood's lamp, a biochemical blood test for vitamin D and A. Results and discussion: it was found that the course of Cannon's spongy nevus is cyclic, periods of exacerbation and remission replace each other within 10-14 days. The results of luminescent diagnostics turned out to be non-specific - the mucous membrane of the oral cavity under ultraviolet rays is gray-white in color, which is typical for hyperkeratosis. Vitamin D in the blood of patients with Cannon's spongy nevus is reduced, and vitamin A is within the normal range. Conclusions: a cyclical course, similar symptoms in relatives under 30 years old, young age, low vitamin D in the blood are diagnostic criteria for Cannon's spongy nevus, and the frequency of exacerbations increases with nervous tension.