Abstract
Extracellular vesicles (EVs) are critical mediators of intercellular communication, playing vital roles in various physiological and pathological processes. These nanometer-sized vesicles, which include exosomes, microvesicles, and apoptotic bodies, carry proteins, lipids, and nucleic acids that relay biological information between cells. Exosomes, ranging from 30 to 150 nm, are particularly important in cell signaling, immune regulation, and tissue regeneration. EVs have been implicated in the progression of diseases such as cancer, neurodegenerative, and cardiovascular diseases, showcasing their potential as diagnostic biomarkers and therapeutic tools. For instance, stem cell-derived EVs promote tissue regeneration, whereas cancer cell-derived EVs facilitate tumor growth and metastasis while aiding immune evasion. Recent studies indicate that EVs can be used to rejuvenate aged cells and mitigate age-related diseases. However, several challenges remain in EV research, such as the lack of standardized methods for isolation and characterization, as well as issues related to heterogeneity and clinical scalability. Advancing techniques for large-scale production and safety assessments is crucial for their clinical translation. Understanding the multifaceted roles of EVs is essential for future diagnostic and therapeutic innovations.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
