Abstract
Cortico-cortical evoked potential (CCEP) mapping is an emerging method for mapping functional connectivity in brain network. It has several advantages over conventional brain stimulation in cooperation, time, and seizure risk. However, the applications of CCEP are not well-established in epilepsy surgery. We investigated the CCEP mapping of the language network in a patient with left temporal lobe epilepsy. CCEPs were obtained from perisylvian cortex time-locked to the stimulus. Stimulation at Broca’s area elicited early and late CCEPs in the posterior part of the superior temporal gyrus, matching the previous mapping from the direct cortical stimulation. Verification of the language network by CCEP gave a helpful information for determining the lateral extent of resection confidently. Postoperatively the patient had neither language deficits nor further seizures. The evaluation of language network by CCEP mapping could be useful in epilepsy surgery near language area.
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