Abstract
The article presents results of the studies on assessment of the effect of a number of biologically active feed additives on leukocyte formula structure of African sharptooth catfish. The biologically active feed additives under study were: "Irkutin" adaptogen, "Sporothermin" probiotics and "Chiktonik" vitamin - amino acid complex. Until recently, adaptogenes have not been used in fish feeding, but they are widely used in medicine to increase nonspecific resistance and resistance to stress. We evaluated the effect of the adaptogenes on leukocyte formula structure of African sharptooth catfish. The effect of "Chiktonik" vitamin-amino acid complex and "Sportermin" probiotics based on B. subtilis and B. licheniformis bacteria on the leukocyte formula of African catfish was also evaluated. The probiotics was used to regulate the microbiocenosis of fish gastrointestinal tract. The vitamin-amino acid complex was used to improve fish metabolism. In the course of the work, it was found that "Irkutin" adaptogene had the most pronounced effect on leukocyte formula structure among all the studied biologically active feed ingredients. Analysis of the leukocyte formula in case of usage of biologically active feed ingredients revealed activation of the phagocytic link. In case of application of each of the biologically active feed ingredients, a specific redistribution of the content of lymphocytes, neutrophils, monocytes and other cells in the leukocyte formula of African catfish took place. The research results showed that biologically active feed ingredients: "Irkutin" adaptogene, "Sportermin" probiotics, "Chiktonik" vitamin-amino acid complex showed an immunomodulatory effect.
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