Abstract

Serological monitoring has been conducted worldwide for early diagnosis of disease and monitoring of immune status in poultry. This study was conducted to evaluate the immune status of layers with sera submitted to the Avian Disease Laboratory, Chungbuk National University from 2015 to 2017. The test results were analyzed by the time submitted and by the age of the chicks. Low pathogenic avian influenza (LPAI) showed a low positive rate of antibody compared with those of Newcastle disease, indicating that domestic vaccination against LPAI was not sufficient. The antibody profile of infectious bronchitis (IB) depicted high level of titer and a low tendency of CV as compared to the uninfected control flocks, which indicated that most layer farms have been exposed to the field IB virus. In case of avian metapneumovirus infection (aMPV) and <italic>Mycoplasma synoviae</italic> (MS), since the introduction of the vaccine in 2011 and 2017, respectively, the positive rate and the titer level were higher than those in pevious times. No significant difference in the changes of seasonal result was observed, indicating proper vaccination and improvement in biosecurity and management.

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