Abstract
Immunosensors and immunotests are commonly used in medicine, where blood, urine or saliva samples enable concentrations of morphine, progesterone, estradiol, dopamine, insulin to be determined.In this work, the use of immunosensors for the following medical problems is considered: for the quantitative detection of alpha-fetoprotein, for determination of p53 protein in urine for diagnostics bladder cancer, for amperometric determination of carcinoembryonic antigen, for the determination of galectin-3, as biomarker of heart failure, for detecting hepatitis B surface antigen, for sensitive detection of tumor marker for determination of serum level in breast cancer patients.
Highlights
Immunosensors are affinity ligandbased biosensor solid-state devices in which the immunochemical reaction is coupled to a transducer
Further we present the most widely used immunosensors together with their characteristics
A new dual mode competitive immunosensing platform for sensitive determination of AFP combined photoelectrochemical and electrochemical methods was designed on graphite carbon nitride and reduced graphene oxide (g-CN/rGO) conjugate support. To construct such versatile support, polyamidoamine dendrimer (PAAD) decorated graphene oxide as substrate was reduced via poten-tiostatic technology, and the prepared rGO-PAAD nanocomposite was utilized as matrix to immobilize g-CN and capture antigen, and as electron transporter to mediate electron transfer for enhancement of photoelectrochemical and electrochemical signals
Summary
STUDY OF CLASSIFICATION OF IMMUNOSENSORS FROM VIEWPOINT OF MEDICAL TASKS V. The use of immunosensors for the following medical problems is considered: for the quantitative detection of alpha-fetoprotein, for determination of p53 protein in urine for diagnostics bladder cancer, for amperometric determination of carcinoembryonic antigen, for the determination of galectin-3, as biomarker of heart failure, for detecting hepatitis B surface antigen, for sensitive detection of tumor marker for determination of serum level in breast cancer patients. В данной работе рассматривается использование иммуносенсоров для следующих медицинских проблем: количественного определения альфа-фетопротеина, определения белка р53 в моче с целью диагностики рака мочевого пузыря, амперометрического определения карциноэмбрионального антигена, определения галектина-3 как биомаркера сердечной недостаточности, выявления поверхностного антигена гепатита В, чувствительного детектирования маркера опухоли при определении уровня в сыворотке крови пациентов с раком молочной железы.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
