Abstract
*Department of Medical Biomaterials Engineering, Kangwon National University, Chuncheon 200-701, Korea.**Department of Food Science and Engineering, Seowon University, Cheongju 361-742, Korea.ABSTRACT : This research evaluate antioxidant and skin-whitening effect of Abeliophyllum distichum Nakai by extractionprocesses. First, antioxidant effects were follows: EE (70% ethanol extract) showed higher DPPH scavenging activity of69.66% than WE (hot water exract) 59.13% at 0.3 ㎎/㎖, also UE's (70% ethanol extract by sonication process) higher thanEE. Reducing power was that also EE showed higher than WE, and it was the highest value with UE's because of ultrasonicpretreatment. Next, the whitening effect tyrosinase inhibition activity was measured that EE was 23.88%, WE's was16.69%, and UE was 23.34%. Ultrasonic pretreatment did not influence to tyrosinase inhibition activity. Cell viabilityshowed low cell toxicity in all groups. UE's inhibited melanin synthesis, 55.1%, that is higher than EE and WE, 52.7% and39.5%, respectively. As a result, we confirmed that antioxidant activities and skin-whitening effect by extraction process.Also, this results confirmed that the Abeliophyllum distichum Nakai extracts worth as cosmetic materials. Key Words : Antioxidant, Skin-Whitening, Abeliophyllum distichum , Melanin
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