Abstract

The intestinal microflora largely determines the immune system, so it is important to maintain its condition and balance in the norm. This requires a detailed understanding of the characteristics of the environment in which it grows and develops. Prebiotics are used to maintain the intestinal microbial pool. The prebiotic fructose-oligosaccharide lactulose has a pronounced bifidogenic effect. It is safe, technologically advanced, and is available in syrupy and crystalline forms. Lactulose is included in the list of essential medicines of the World Health Organization. The purpose of these studies is to determine the effect of the prebiotic lactulose on the pH of the pH of the chyme of different parts of the gastrointestinal tract of rabbits. The control and experimental groups of male rabbits of the California breed were formed by a meth of pairs of analogues of 20 heads each. The activity index of hydrogen ions was determined by the pH of the chyme of the stomach, small intestine, caecum, appendix, colon, and rectum. An average sample of chyme was taken. Based on the data obtained, it was found that the introduction of lactulose in the diet of California rabbits at a dosage of 0.06 g per 1 kg of live weight acidifies the contents of the stomach, caecum and rectum, and in the contents of the small part, the appendix and the colon, where the reaction of the medium is alkaline, reduces the alkalinity, shifting the pH value to the acidic side.

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