Abstract
Lasers are generating systems that implement the extreme concentration of the emitted energy in the spectrum, space and time. Heating of biological tissues by electromagnetic radiation, including powerful infrared laser radiation, can cause of their destruction: evaporation, sublimation and dissection. Blood circulation causes efficient cooling, and mechanical pressure tissueinduces intensive penetration of the laser radiation with lower loss of coherence.
 The special series of surgical instruments has been developed, patented and used in practical activities for 4 decades. Theinstruments allowed to reaching a mechanical compression of tissue, positioning and moving the laser beam, locally block the blood circulation, the optimal regimes of laser surgical exposure of tissues were estimated by using the real thermo-physical characteristics for different tissues.
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