Abstract
The number of people suffering from endocrine disorders is increasing. The interaction between diseases such as diabetes and various thyroid diseases is of some interest. This article presents the results of investigating the effect of different thyreopathies on carbohydrate metabolism and lipid profile, which may have some significance for the possible management tactics of these patients. Objective. To demonstrate clinical and laboratory features of carbohydrate metabolism disorders in different thyroid diseases. Patients and methods. Patients were examined during the period 2021–2022, among them were patients with thyroid diseases: hypothyroidism, thyrotoxicosis, endemic goiter without dysfunction. A total of 257 patients were examined, including 96 patients with hypothyroidism, 29 with thyrotoxicosis, and 93 with endemic goiter, as well as 38 patients without thyroid diseases (the control group). Results and discussion. When comparing the results of plasma glucose and glycated hemoglobin (HbA1c) tests for all groups, a significant increase in their levels was revealed. Patients with hypothyroidism were found to have higher cholesterol levels compared to the control group, and significant differences were also established in the evaluation of low-density lipoproteins in patients with endemic goiter. Conclusion. Various thyroid diseases lead to certain metabolic disorders, namely, deterioration of carbohydrate metabolism and a slight deterioration of lipid profile. Key words: thyroid gland, carbohydrate metabolism, endemic goiter, hypothyroidism, thyrotoxicosis, euthyroidism, lipid metabolism
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