Abstract

Objectives We aimed to identify the effectiveness of photobiomodulation using low level laser therapy (LLLT), emitting diode (LED) and others on the of the length of the by reviewing literatures. Methods We searched literatures using PubMed, Science Direct, CINAHL, Korea Traditional Knowledge Portal (KTKP), Oriental Medicine Advanced Searching Integrated System (OASIS), China Knowledge Resource Integrated Database (CNKI), Japan Science and Technology Information Aggregator, Electronic (J STAGE), and Japan National Institute of Informatics Scholarly and Academic Information Navigator (CiNii) using the keywords Growth plate Epiphyseal growth Epiphyseal plate and Laser, light emitting diode (LED), near-infrared light, and photobiomodulation. Search range included only original article which provided English abstract were selected. The search strategy contained no language limitation. Results A total 556 studies were found. Then, 551 were excluded by scanning titles and abstracts and finally 5 articles were selected. Five articles were RCTs using rodents. Two of the 5 articles used InGaAlP Laser (630-685 nm), and the other 3 articles used GaAlAs Laser (780, 820, and 870 nm) to investigated the effects of LLLT on the of the length of the epiphyseal cartilage and the number of chondrocytes and thickness of each zone of the epiphyseal cartilage. Two articles concluded that LLLT had a beneficial effect on the longitudinal of the plate. In of the epiphyseal plate, there were no significant differences in others. Conclusions It is might that LLLT influenced on the of epiphyseal by positive affect. However, further rigorous RCTs are warranted.

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