Abstract
Propolis and honey are beekeeping products and are widely used as health supplements for humans. Previous studies have shown that propolis and honey have various physiological properties, including antioxidant, anti-inflammatory, and antibacterial effects. In order to investigate the physiological response induced by propolis and honey, including developmental time (larval and pupal periods), reproductivity, and adult lifespan (both male and female), we treated Drosophila melanogaster, a representative model organism, with these beekeeping products. We observed alterations in developmental time, adult longevity, and reproductivity in D. melanogaster treated with either propolis or honey. Interestingly, when honey or propolis induces an increase in oviposition, the survival rate of female adults tended to decrease. However, when female D. melanogaster were fed with propolis the oviposition rate remained constant and, the extended longevity was observed. In this study, we provided insight into the physiological activity of honey and propolis through the Drosophila model, and future follow-up studies are expected to elucidate their molecular physiological mechanisms.
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