Abstract

We compared two metered-dose local sprays containing hexethidine: Maxicold LOR and StopanginTeva. We evaluated the parameters reflecting spray quality, including reproducibility of the dose mass and the irrigation area on planar simulation models. Both sprays demonstrated almost equal high reproducibility of the dose mass. The spray width of Maxicold LOR was larger than that of StopanginTeva, while the spray patterns and reproducibility of print area on the simulation model were similar for both sprays. Key words: hexetidine, metered-dose local sprays, sore throat, simulation model, reproducibility of the dose mass, irrigation area

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