Abstract

The article presents the experience of the project on physical and psychological recovery of families after reproductive losses. The concept of fetal loss syndrome was chosen as a principle of the project, which provides both common pathogenetic mechanisms of early and late miscarriage, spontaneous and induced premature birth, which lead to neonatal death, and similar mechanisms of psychological experience of reproductive loss due to the lack of formed connection between parents and child. The main etiological factors of miscarriage, the principles of their diagnosis and the applied algorithm of treatment are considered. In particular, a detailed description of the role of progesterone deficiency in the mechanisms of miscarriage and severe obstetric complications is given, the debatability of the effectiveness of unjustified prescribing of exogenous progesterone, both from a molecular and epidemiological point of view. Attention is paid to thrombophilias of various origins, which is currently one of the recognized factors of miscarriage. The results of the project are presented, which include more than 20 meetings held in 3 years, as a result of which 20 couples were planned to have the next pregnancy and its observation. All 20 cases were completed in the Perinatal Center by timely delivery with the birth of a living healthy child, so all pregnancies became maternity. Keywords: Kyiv Perinatal Center, miscarriage, reproductive losses, pregnancy, thrombophilia, progesterone deficiency, psychology.

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