어린이와 청소년의 비알콜성음료 섭취에 따른 인공감미료 섭취량 평가

Abstract

aims of this study were to estimate daily intakes of artificial sweeteners from beverages and liquid teas as well as evaluate their potential health risks in Korean children and adolescents (1 to 19 years old). Dietary intake assessment was conducted using actual levels of aspartame, acesulfame-K, and sucralose in non-alcoholic beverages (651 beverages and 87 liquid teas), and food consumption amounts were drawn from The Fourth Korea National Health and Nutrition Examination Survey (2007～2009). To estimate dietary intake of non-alcoholic beverages, a total of 6,082 children and adolescents (Scenario Ⅰ) were compared to 1,704 non-alcoholic beverage consumption subjects (Scenario Ⅱ). estimated daily intake of artificial sweeteners was calculated based on point estimates and probabilistic estimates. values of probabilistic artificial sweeteners intakes were presented by a Monte Carlo approach considering probabilistic density functions of variables. level of safety for artificial sweeteners was evaluated by comparisons with acceptable daily intakes (ADI) of aspartame (0～40 mg/kg bw/day), acesulfame-K (0～15 mg/kg bw/day), and sucralose (0～15 mg/kg bw/day) set by the World Health Organization. For total children and adolescents (Scenario Ⅰ), mean daily intakes of aspartame, acesulfame-K, and sucralose estimated by probabilistic estimates using Monte Carlo simulation were 0.09, 0.01, and 0.04 mg/kg bw/day, respectively, and 95th percentile daily intakes were 0.30, 0.02, and 0.13 mg/kg bw/day, respectively. For consumers-only (Scenario Ⅱ), mean daily intakes of aspartame, acesulfame-K, and sucralose estimated by probabilistic estimates using Monte Carlo simulation were 0.52, 0.03, and 0.22 mg/kg bw/day, respectively, and 95th percentile daily intakes were 1.80, 0.12, and 0.75 mg/kg bw/day, respectively. For scenarios Ⅰ and Ⅱ, neither aspartame, acesulfame-K, nor sucralose had a mean and 95th percentile intake that exceeded 5.06% of ADI.