Abstract
Acute kidney injury in polytrauma is a common and serious complication that significantly worsens the prognosis. Objective: to evaluate the effect of hemodialysis (HD) with high-permeability membranes on the reduction of myoglobin in polytrauma and rhabdomyolysis complicated by acute kidney injury in comparison with plasmapheresis and high-volume hemodiafiltration. Methods: 18 patients with increased creatine phosphokinase (CPK) above 5000 U/E and myoglobin above 1000 ng/ml, stage 3 AKI. The severity of polytrauma was assessed according to the AIS–ISS criteria. The patients were male, from 27 to 47 years old. Results: The average decrease in myoglobin during highflow extended hemodialysis for 2 hours was 31.25% Conclusion: High-flow extended hemodialysis is an alternative method that removes myoglobin and is superior to hemodiafiltration and plasmapheresis in its removal.
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