Сучасний стан фіксації тканин в ортопедії та травматології

Abstract

Peculiarities of bone tissue remodeling processes affect the use of the latest molecular and cellular methods of fracture treatment, in particular, the use of biological glue. Currently, adhesive materials are used in surgery quite widely, but it is important to soberly assess the current state of tissue fixation methods in orthopedics and traumatology. Medical adhesives are special type of polymer alloimplants. Their main purpose is a strong connection of living tissues with an optimal ratio between good adhesive properties, speed of biodestruction and minimal inflammatory reaction. The most common adhesives used in surgery are: polyurethanes, cyanoacrylates, epoxies, and adhesives based on a mixture of natural and synthetic rubbers. It is important to separately discuss the glue, which is used not only in orthopedics and traumatology, but also in neurosurgery, maxillofacial surgery, vertebrology, cardiac surgery, thoracic surgery and dentistry. It is a bone replacement material called Kryptonite. Biological glue Bio Glue is a surgical glue intended for sealing and strengthening surgical sutures and gluing tissues together. Casein glues belong to the class of alkaline glues that turn into jelly and take a solid form. Surgical glue “Cryofit” – fibrinthrombin sealant creates a positive environment for the attachment, differentiation and survival of transplanted cells, excludes the possibility of their uncontrolled migration. PRF (Platelet Rich Fibrin) is fibrin rich in platelets obtained from blood by centrifugation. Depending on the blood processing protocol, i-PRF is obtained – injectable fibrin rich in platelets. A less well-known synthetic medical glue is the ZRF system (gelatin-resorcinol-formaldehyde composition). In the works of Braunwald N.S. etc. and Tatooles C.J., Braunwald N.S. it is shown that the glue reliably connects tissues in a humid environment, has a lower histotoxic effect, and is quickly absorbed. The current state of using medical glue as the main (and not additional) method of tissue fixation has significant prospects. It is important to continue studying the properties of materials to achieve the highest results in gluing living tissues.