Abstract
Purpose: to report the first case of the same day use of a single donor cornea tissue for 5 consecutive transplantations in patients with endothelial dystrophy and keratoconus. Material and methods. The Descemet membrane (DM) and the endothelium were fully detached from the stroma of the donor on the endothelial side, using first a circular and then a direct corneal cutter, forming four partial triangle-shaped Descemet grafts (each constituted a 1/4 Descemet graft). The stroma of the donor's cornea was separated by a circular cutter of a preset diameter. One patient with keratoconus underwent deep anterior lamellar keratoplasty (DALK) using the big bubble technique. Then, each of the four Descemet grafts was sequentially transplanted by the Descemet membrane endothelial keratoplasty (DMEK) method to 4 patients with Fuchs dystrophy and pseudophakia. Results. During and after the surgery, there were no complications requiring additional intervention. Six months after DALK, the best corrected visual acuity (BCVA) was 0.66. Six months after four operations each using ¼ DMEK the average BCVA was 0.95 ± 0.1 (from 0.8 to 1.0) and the endothelial cell density was, respectively, 2839 after DALK and 1680 ± 254 cells/mm2 (from 1492 to 2039 cells/mm2) after ¼ DMEK. Conclusion. One donor cornea can be successfully transplanted to at least 5 patients. Despite the fact that the implementation of DALK and several operations using the ¼ DMEK technique within one day is technically difficult, this approach can contribute to a drastic reduction in the deficit of donor tissue. This approach requires a thorough selection of patients and an extensive surgical experience. For citation: Oganesyan O.G., Makarov P.V., Grdikanyan А.А., Getadaryan V.R. A new strategy of keratoplasty: laminating and splitting the donor cornea. Russian ophthalmological journal. 2018; 11 (3): 11-8 (In Russian). doi: 10.21516/2072-0076-2018-11-3-11-18. The full English version is available online at http://roj.igb.ru/eng/issues
Highlights
Цель работы — описать первый случай применения одной донорской роговицы для 5 последовательных трансплантаций в течение одного дня у пациентов с эндотелиальной дистрофией и кератоконусом
âåäóùèé íàó÷íûé ñîòðóäíèê îòäåëà òðàâìàòîëîãèè è ðåêîíñòðóêòèâíîé õèðóðãèè Ï.Â. Ìàêàðîâ
âåäóùèé íàó÷íûé ñîòðóäíèê îòäåëà òðàâìàòîëîãèè è ðåêîíñòðóêòèâíîé õèðóðãèè À.À. Ãðäèêàíÿí
Summary
Цель работы — описать первый случай применения одной донорской роговицы для 5 последовательных трансплантаций в течение одного дня у пациентов с эндотелиальной дистрофией и кератоконусом. Д. На наш взгляд, наиболее быстрым и очевидным способом увеличения количества трансплантаций является рациональное и экономное использование донорской ткани, внедрение современных методов кератопластики, а также индивидуальный подход к хирургии роговицы в каждом клиническом случае [4]. ЦЕЛЬ работы — описать первый случай применения одной донорской роговицы для 5 последовательных трансплантаций в течение одного операционного дня у пациентов с эндотелиальной дистрофией и кератоконусом. В послеоперационном периоде фиксировалось количество и характер осложнений, показатели максимально корригированной остроты зрения (МКОЗ) и плотности эндотелиальных клеток (ПЭК) спустя 6 мес после операции.
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