Токсоплазмозний хоріоретиніт у підлітка: опис власного клінічного випадку

Abstract

Toxoplasmosis is a zoonotic protozoal disease caused by the intracellular parasite Toxoplasma gondii and is characterized by a polymorphism of clinical symptoms with predominant involvement of the nervous, lymphatic systems, eyes, skeletal muscles and myocardium. Despite the variety of therapeutic agents, the treatment of toxoplasmosis remains problematic and requires an interdisciplinary approach. Complete the release of toxoplasmas from the body is difficult, although theoretically possible. This process depends on the combination of individual characteristics of local and general immunity of the macroorganism, the amount of the pathogen and its virulence. Purpose - to present a clinical case of the patient with chorioretinitis as an example of a clinical manifestation of toxoplasmosis infection. Clinical case. The girl turned to an ophthalmologist with complaints of worsening vision and red eyes. After a doctor’s examination, an ophthalmoscopy was performed, the presence of two chorioretinal foci in both eyes was confirmed. Examination for TORCH-infection is recommended. An elevated level of IgM and IgG to Toxoplasma gondii was detected. The patient received a course of antibacterial and hormonal therapy with a positive effect. After 8 months, the girl’s complaints resumed, signs of synovitis of the knee joints appeared, and anemic syndrome joined. During repeated ophthalmoscopy, three chorioretinal foci were found. The girl was hospitalized in the ophthalmology department for a more detailed examination and to decide on further observation tactics. Conclusions. A case of chorioretinitis as a clinical manifestation of toxoplasmosis infection in adolescence is described. Timely diagnosis and started therapy of the above-described pathology are the key to a satisfactory prognosis for recovery, prevention of the development of negative consequences of this disease. The research was carried out in accordance with the principles of the Helsinki Declaration. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors.