Abstract

The article presents the results of studies obtained in the study of the comparative effectiveness of infusion therapy in the treatment of dogs with pyroplasmosis. Piroplasmosis of dogs is a seasonal, acute, blood–parasitic disease of dogs, which is characterized by fever, liver damage, and destruction of red blood cells. Competent and timely implementation of rehydration infusion therapy for pyroplasmosis is an important component in the complex therapy of sick animals, therefore, the study of the comparative effectiveness of traditional and the introduction into veterinary practice of promising medical detoxification infusion drugs is timely and relevant. In this regard, the aim of the research is to study the comparative effectiveness of infusion therapy in the treatment of dogs with pyroplasmosis. The object of the study were dogs of various breeds with pyroplasmosis and documentation reflecting the state of the incidence of pyroplasmosis of dogs in Rostov–on-Don. To confirm the diagnosis, paired blood serums for serological diagnostics, as well as blood and urine samples for biochemical analysis were sent to the veterinary diagnostic center "Invitro" in Rostov-on-Don. To conduct the experiment (according to the principle of analogues), 3 groups of animals were formed, 5 dogs in each. Treatment of dogs with pyroplasmosis was carried out in a complex, with the mandatory appointment of etiotropic and pathogenetic therapy. The effectiveness of treatment of dogs of the experimental groups was evaluated in dynamics compared with the control group. In the process of implementing the tasks of the experiment, generally accepted methods were used, in accordance with GOST standards, satisfying the objectives of the study. Based on the studies conducted to study the effectiveness of infusion therapy in the treatment of dogs with piroplasmosis, it was found that the use of the drug Reamberin allowed to shorten the recovery period compared to the control group by 5 days, with 1 experimental group – by 2 days. The drug Reamberin has proven to be the most effective infusion drug with antioxidant, hepatoprotective and detoxifying effects.

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