Abstract
ABSTRACT Review on the Acne Related Articles Published in Korean Medical Journals- Focusing on Experimental Studies Published after 2005 -Hee-Jung Yoon, Dong-Il KimDept. of OB & GY, College of Korean Medicine, Dong-Guk UniversityObjectives: This study was performed to analyze the trend of acne-related experimental studies in Korean medicine. Methods: We searched 17 articles related with experimental study of acne , published Korean medical journals from 2005 to 2014. We classified all articles according to the journal and checked on the kind of herbs. All articles were categorized into two types: cell experimental study and animal experimental study. Results: 1. Total 17 papers were searched; 7 articles (41.2%) were publi shed in the Journal of Korean Medical Ophthalmology, Otolaryngology, Dermatology, 4 articles (23.5%) were published in the Journal of Korean Institute of Pharmacopu ncture, 3 articles (17.6%) were published in Korean Journal of Oriental Physiology and Pathology, 2 articles (11.8%) were published in Korean Journal of Herbology, and 1 article (5.9%) was published in the Journal of Korean Medicine.2. Total 17 kind of herbs were used in the studies; 10 articles (58.8%) used single herb, 7 articles (41.2%) used complex herbs. 3. Total 17 articles were categorized 2 types; 16 cell experime ntal studies (94.1%), 1 animal experimental study (5.9%).4. Experimental researches were mainly investigated using Raw 2 64.7 cell line and P. acnes. The levels of NO, iNOS, TNF- α, PGE, COX-2, IL-1β, IL-6, NF-kB were analyzed to confirm of herbs’ antibacterial, anti-inflammatory, antioxidant activity. Conclusions: Searching for natural antibiotics, it is needed to do experime ntal studies continuously, and also needed to diversify the kind her bs and experimental bacteria. Key Words: Acne, P. acnes, Anti-inflammation
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