Стан стовбуромозкового відділу слухового аналізатора при цукровому діабеті 2-го типу і порушеннях слухової функції

Abstract

The purpose of our study is to examine the condition of brainstem part of the auditory analyzer based on examination of the short-latent auditory evoked potentials (SLAEP) in 43 patients with diabetes mellitus (DM) type 2 with disorders of auditory function. We revealed sensorineural hearing loss (SNHL) of the I-II degree according to the internation- al classification. The registration of SLAEP was conducted by the system «Eclipse» «Interacoustics» (Denmark). We detected a lengthening of the latent periods of the peaks (LPP) of the II, III, IV and V waves of SLAEP, as well as the inter-peak intervals of I-III and I-V comparing to the control values. So, LPP of III wave SLAEP was 3.85 ± 0.04 ms, and of V wave was 5.83 ± 0.05 ms. According to the severity of DM type II, we divided the patients into two groups: without (group I) and with (group II) complica- tions. A comparative analysis revealed that the values of LPP III wave and also I-III in group 2 not only significantly exceeded the normal values, but also significantly differed from the same indicators in group 1. Thus, the LPP of the III wave of SLAEP was 3.81 ± 0.03 and 3.95 ± 0.05 ms, in group 1 and 2, respectively. In group 2 inter-peak interval I-III was 2.29 ± 0.03 ms, inter-peak interval I-V was 4.21 ± 0.04 ms. This indicates the possible influence of the complicated course of diabetes mellitus II on the development of disorders in the central departments of the auditory analyzer, particular in its brainstem structures. Therefore, among all studied groups of patients with SNHL on the background of DM type II there are a pronounced deviations from the norm in the state of the brainstem part of the auditory analyzer. The obtained data indicate an important role of the state of brainstem part of auditory analyzer in the development of sensorineural hearing disorders in diabetes mellitus type II.