Abstract
The article presents the results of studies of α-defensin level in chronic adenoiditis in children. The purpose — to assess the state of innate mucosal immunity in chronic adenoiditis. Material and methods. We examined 151 patients with chronic adenoiditis aged 3 to 7 years. Concentration of α-defensin was determined using the HBT Human HNP 1-3 ELISA kit, designed for the quantification of neutrophil defensins in mixed saliva. Results. The analysis showed that in both groups of children with chronic adenoiditis there was a statistically significant (p < 0.05) increase in the concentration of defensins in saliva compared to the age norm.
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