Оцінка ефективності корекції вегетативних розладів та психоемоційного стану вагітних

Abstract

The objective: is to investigate the clinical efficacy of the proposed treatment complex, which contains a unique combination of 3 active substances (Ginkgo biloba, Omele white, Hedi) in correction of autonomic and psychoemotional disorders in pregnant women with autonomic dysfunction. Materials and methods. Pregnant women with established autonomic dysfunction were divided into 2 clinical groups: the main (group I) and the comparison group (group II). Patients in the main group (n=30) were assigned the proposed treatment complex.The comparison group consisted of 30 pregnant women with autonomic disorders that did not differ by age, sex, body mass index, and received only standard drug therapy. The drug was given to pregnant women in a dose of 20 drops 3 times a day. The course of therapy was one month and repeated 2 times in the first and second half of the pregnancy at intervals of 4–6 weeks. To assess the autonomic state the Wein questionnaire and cardiointervalography indicators were used before and after the treatment. The psychoemotional state was determined by the Spielberger-Khanin scale. Results. Under the influence of the proposed therapy, particular attention should be paid to the reduction of such manifestations of autonomic dysfunction as headache, tides, sweating, fatigue, palpitations, emotional lability and insomnia. The main group noted improvement in mental and physical activity, mood changes and a decrease in overall asthenia. The severity of autonomic disorders significantly decreased, an improvement in the general condition of pregnant women was observedafter receiving the prescribed medication. A significant decrease in number of women ofI group with a Wein score >25 was established – from 71.7% to 23.3%. After the course of treatment, according to cardiointervalography, in pregnant women of the main group the normotonic autonomic state was registered, the frequency of sympathotonia and parasympathotonia decreased. A significant increase from 48.3% to 86.6%of pregnant women with norm-adaptive regulatory state, marked reduction of anxiety and restoration of normal psycho-emotional state was notedin the I groupafter the treatment. The application of the proposed complex improved the course of pregnancy and childbirth in patients of the main group compared to women of the II group. Conclusions. Treatment according to the proposed scheme reduced the severity of autonomic disorders, perinatal complications and improved the course of labor in patients of I group. Application of the offered medical complex in pregnant women with autonomic dysfunction has a stabilizing effect along with the absence of side effects, which significantly extends the scope of the proposed therapy in pregnant women at different gestational periods. Key words: autonomic dysfunction, psychoemotional state, adaptation, pregnancy, labor, cardiointervalography, Ginkgo biloba, Omele white, Hedi.