Abstract
A retrospective cohort study of postponed outcomes of surgical treatment of patients with pulmonary tuberculosis was conducted; all patients lived in the region with a high prevalence of the disease (the Republic of Altai) and were treated during the period from 2004 to 2014. All patients (n = 215) had indications for surgical treatment. The main group included 111 patients who underwent surgery further on, while the comparison group included 104 patients who rejected the proposed surgery for various reasons. Outcomes were analyzed in 3-9 years after indications for surgical treatment were identified, depending on the clinical form of tuberculosis and type of surgical intervention. It was found that the lung resection as a part of the comprehensive treatment of patients with pulmonary tuberculomas allowed achieving clinical cure in a confidently bigger number of cases (97.1%) compared to those who rejected surgical treatment (80.0%, p = 0.003; χ2). Clinical cure after resections due to fibrous cavernous tuberculosis was achieved in 90.0% of patients, and only in 44.4% of those who refused surgical treatment (p = 0.02; two-sided Fischer’s Exact test). Collapse surgery allowed achieving clinical cure in 62.5% of cases with disseminated fibrous cavernous pulmonary tuberculosis, while conservative treatment provided clinical cure only in 8.6% of cases (p = 0.0001; two sided Fischer’s Exact test); the mortality made 6.3 and 42.8%, respectively (p = 0.01; two-sided Fischer’s Exact test).
Highlights
Проведено ретроспективное когортное исследование отдаленных результатов хирургического лечения больных туберкулезом легких, проживающих в регионе с высокой распространенностью заболевания (Республика Алтай) и получавших лечение в период с 2004 по 2014 г
A retrospective cohort study of postponed outcomes of surgical treatment of patients with pulmonary tuberculosis was conducted; all patients lived in the region with a high prevalence of the disease and were treated during the period from 2004 to 2014
Outcomes were analyzed in 3-9 years after indications for surgical treatment were identified, depending on the clinical form of tuberculosis and type of surgical intervention
Summary
В которое включено 215 пациентов. Все пациенты проживали в Республике Алтай и в период с 2004 по 2014 г. были проконсультированы фтизиохирургом, им было предложено хирургическое лечение (момент включения в исследование). Были проконсультированы фтизиохирургом, им было предложено хирургическое лечение (момент включения в исследование). На момент определения показаний к хирургическому лечению бактериовыделение прекратилось у 31 (41,9%) и 24 (31,6%) пациентов (p = 0,19; χ2) 1-й и 2-й групп соответственно. На момент определения показаний к хирургическому лечению туберкулема легкого диагностирована у 74 (66,7%) и 60 (57,7%) больных 1-й и 2-й групп, ФКТ сформировался у 37 (33,3%) и 44 (42,3%) соответственно (p = 0,17; χ2) Среди больных ФКТ резекция легкого была показана 21/37 (56,8%) пациенту 1-й группы и 9/44 (20,5%) – 2-й (p = 0,001; χ2). У остальных больных ФКТ – 16/37 (43,2%) и 35/44 (79,5%) в 1-й и 2-й группах – распространенность туберкулезного процесса, прогрессирующее течение заболевания явились противопоказаниями к радикальному вмешательству и были установлены показания к коллапсохирургическим вмешательствам. В зависимости от предложенной операции во время включения в исследование больные обеих групп разделены на три подгруппы.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
