Abstract
The study aims to assess the effect of a two-hour inhalation with a krypton and oxygen mixture following the photo-induced cerebral infarction simulation on the manifestation of neurological deficits and the degree of brain injury in rats. The tests were conducted on male Wistar rats weighting 250 to 300 g (n = 20). Following photo-induced cerebral infarction simulation, the rodents underwent inhalation with a nitrogen and oxygen mixture N2 70%/O2 30% (group Nitrogen; n = 10) or a krypton and oxygen gas mixture Kr 70%/O2 30% (group Krypton; n = 10) for two hours. For the next 14 days, the rats were examined. On the 3rd, 7th, and 14th days, the authors performed a neurological test Limb placement, as well as euthanasia and brain removal for histological and mmunohistochemical examinations. It was determined that a two-hour inhalation with a krypton and oxygen gas mixture substantiated more prominent rehabilitation of rats’ neurological states by the seventh day, as well as increased the reparation and regeneration of their injured brains.
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